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     Advance Journal of Food Science and Technology


Determination for Synthesis and Content of Tetrahydropalmatine Based on High Performance Liquid Chromatography

Yuanming Zhang
Laboratory of New Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao 266071, P.R. China
Advance Journal of Food Science and Technology  2014  10:1100-1103
http://dx.doi.org/10.19026/ajfst.6.167  |  © The Author(s) 2014
Received: September 16, 2013  |  Accepted: September ‎04, ‎2014  |  Published: October 10, 2014

Abstract

Tetrahydropalmatine is a kind of food additive with useful medicine value (dietary supplement), the tetrahydropalmatine synthetic process by using high performance liquid chromatography method was researched in the study, the experiments show that the dissolution rate of active ingredients in the tetrahydropalmatine water extract synthesized by this method has increased and the amount of active ingredient has greatly improved.

Keywords:

High performance liquid chromatography, synthesis, tetrahydropalmatine,


References

  1. Caslavska, J. and W. Thormann, 2011. Stereoselective determination of drugs and metabolites in body fluids, tissues and microsomal preparations by capillary electrophoresis (2000-2010). J. Chromatogr. A, 1218: 588-601.
    CrossRef    PMid:20869061    
  2. Du, F.Y., T. Liu, T. Shen, F. Zhu and J. Xing, 2012. Qualitative-(semi)quantitative data acquisition of artemisinin and its metabolites in rat plasma using an LTQ/Orbitrap mass spectrometer. J. Mass Spectrom., 47: 246-252.
    CrossRef    PMid:22359336    
  3. Ferrer, I. and D. Barceló, 1999. Validation of new solid-phase extraction materials for the selective enrichment of organic contaminants from environmental samples. TrAC-Trend. Anal. Chem., 18: 180-192.
  4. Gao, J.L., T.C. He, Y.B. Li and Y.T. Wang, 2009. A traditional Chinese medicine formulation consisting of Rhizoma Corydalis and Rhizoma Curcumae exerts synergistic anti-tumor activity. Oncol. Rep., 22: 1077-1083.
    PMid:19787224    
  5. Hong, Z.Y., J. Le, M. Lin, G.R. Fan, Y.F. Chai, X. Yin and Y.T. Wu, 2008. Comparative studies on pharmacokinetic fates of tetrahydropalmatine enantiomers in different chemical environments in rats. Chirality, 20: 119-124.
    CrossRef    PMid:18074336    
  6. Huang, X.D., F. Qin, X.M. Chen, Y.Q. Liu and H.F. Zou, 2004. Short columns with molecularly imprinted monolithic stationary phases for rapid separation of diastereomers and enantiomers. J. Chromatogr. B, 804: 13-18.
    CrossRef    PMid:15093154    
  7. Oliferova, L., M. Statkus, G. Tsysin, O. Shpigun and Y. Zolotov, 2005. On-line solid-phase extraction and HPLC determination of polycyclic aromatic hydrocarbons in water using ?uorocarbon polymer sorbents. Anal. Chim. Acta, 538: 35-40.
    CrossRef    
  8. Portmann, S., H.Y. Kwan, R. Theurillat, A. Schmitz, M. Mevissen and W. Thormann, 2010. Enantioselective capillary electrophoresis for identification and characterization of human cytochrome P450 enzymes which metabolize ketamine and norketamine in vitro. J. Chromatogr. A, 1217: 7942-7948.
    CrossRef    PMid:20609441    
  9. Tomori, E., G. Horváth, M. Pátfalusi, S. Mészáros and L. Vereczkey, 1992. Pharmacokinetic and metabolism studies on girisopam by chromatographic and spectrometric methods in humans. J. Chromatogr., 578: 91-101.
    CrossRef    
  10. Wang, B.L., J.P. Hu, W. Tan, L. Sheng, H. Chen and Y. Li, 2008. Simultaneous quantification of four active schisandra lignans from a traditional Chinese medicine Schisandra chinensis(Wuweizi) in rat plasma using liquid chromatography/mass spectrometry. J. Chromatogr. B, 865: 114-120.
    CrossRef    PMid:18339588    
  11. Xing, J.F., M.N. Wang, X.Y. Ma, W.W. Liang and Y.H. Wang, 1997. Effects of dl-tetrahydropalmation on rabbit platelet aggregation and experimental cerebral thrombosis in rats. Chin. Pharmacol. Bull., 13: 258-260.
  12. Xu, P., Y. Su and N. Na, 2013. Effect of grape procyanidins on vascular endothelial cell apoptosis by flow cytometry analysis. Adv. J. Food Sci. Technol., 5(4): 449-452.
    CrossRef    Direct Link

Competing interests

The authors have no competing interests.

Open Access Policy

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Copyright

The authors have no competing interests.

ISSN (Online):  2042-4876
ISSN (Print):   2042-4868
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