Research Article | OPEN ACCESS
Human Cytomegalovirus IgG and IgM Seropositivity among Pregnant Women in Sulaimani City and Their Relations to the Abortion Rates
1Salih Ahmed Hama and 2Kazhal J. Abdurahman
1Department of Biology, School of Science, University of Sulaimani-Iraqi Kurdistan
2Central Laboratory, Sulaimani Health Directorate, Ministry of Health-Iraqi Kurdistan
Current Research Journal of Biological Sciences 2013 4:161-167
Received: January 05, 2013 | Accepted: February 18, 2013 | Published: July 20, 2013
Abstract
This study was aimed to investigate the percentage rates of Cytomegalovirus IgG and IgM seropositivity and their relations to abortion among 185 tested women in Sulaimani city (Iraq) using ELISA technique. The studied cases were included 35 with abortion history, 120 pregnant and 30 controls. The majority of tested women were positive for IgG (90.2%) regardless to the tested groups, the percentage of CMV-IgM positive without IgG was (9.18 %), whereas (7.02 %) were negative for both IgG and IgM. Statistical analysis showed significant relation between CMV-IgM seropositivity and abortion (p = 0.048), whereas no significant relations were found between abortion and CMV-IgG seropositivity (p = 0.512). Significant relations were found between CMV-IgG and IgM seropositivity and changes in some haematological parameters included total white blood cells (p = 0.000) for all three tested groups, significant differences were found for platelets between both pregnant women with and without abortion and controls (p = 0.0206 and 0.0308) respectively. Effects of residency, socioeconomic conditions and previous history of blood transfusion on CMV-IgG and IgM seropositivity were studied and no significant effects were found regarding the tested women groups (p>0.05). No significant effects of CMV-IgG and IgM seropositivity were found on Haematocrit, Lymphocyte, Monocyte and granulocyte counts (p>0.05) for each regarding all three tested women groups.
Keywords:
CMV-IgG, CMV-IgM, HCMV, pregnancy,
Competing interests
The authors have no competing interests.
Open Access Policy
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Copyright
The authors have no competing interests.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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