| Abstract |
Article Information:
Mathematical Modelling on the CDTI Prospects for Elimination of Onchocerciasis: A Deterministic Model Approach
L. Jibril and M.O. Ibrahim
Corresponding Author: Jibril Lawal
Key words: Heterogeneous, ivermectin, linearised, Microfilaria, Oncocerca-volvulus, prospects, Vol. 3 , (4): 141-150 |
| Submitted |
Accepted |
Published |
| 2011 October, 02 |
2011 November, 04 |
2011 December, 15 |
The study incorporated host heterogeneous exposure to Onchocerciasis into four simple
compartmental of both human and vector host regulatory processes, which is of initial value problems of a
systems of ordinary differential equations, with newborns being susceptible, in which both births and deaths
occurs at equal rate. The control of Onchocerciasis currently focuses on Community Directed Treatment with
Ivermectin, CDTI, which effectively kills the Onchocerca volvulus microfilarae in the human hosts. In this
study, the asymptotically stability analysis is determined for the disease free equilibrium and endemic
equilibrium states. Furthermore, on using principles of linearised stability, the study established that the state
of total eradication of Onchocerciasis would be stable and becomes reality if the CDTI control strategies are
maintained throughout the targeted period, hence the population is sustainable. |
Cite this Reference:
L. Jibril and M.O. Ibrahim, 2011. Mathematical Modelling on the CDTI Prospects for Elimination of Onchocerciasis: A Deterministic Model Approach.
Research Journal of Mathematics and Statistics, 3(4): 141-150. |
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ISSN (Online): 2040-7505
ISSN (Print): 2042-2024 |
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