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     Research Journal of Mathematics and Statistics

    Abstract
2011(Vol.3, Issue:2)
Article Information:

Preventing Mother to Child Transmission of Tuberculosis Using Bacillus Calmette-Guérin Vaccine: A Deterministic Modelling Approach

A.I. Enagi and M.O. Ibrahim
Corresponding Author:  A.I. Enagi 
Submitted: 2011 February, 17
Accepted: 2011 March, 15
Published: 2011 May, 25
Abstract:
The must critical stage in the development of a child is the infant stages because their immune system is not yet well developed. At this stage they can easily be infected with Mycobacterium tuberculosis and are also more likely to develop active TB than older people. In this study, we present a mathematical model of effect of bacillus calmette-guérin vaccine in preventing mother to child transmission of tuberculosis. We established the Disease free and the endemic equilibrium states and carried out the stability analysis of the Disease free equilibrium state (the state of complete eradication of Tuberculosis from the entire population). Tuberculosis can be eradicated completely if the total removal rate from the Infectious class is greater than the total number of latent infections produced throughout the infectious period. This can be achieved by effective immunization of new born infants against infection using BCG vacines.

Key words:  Bacillus calmette-guérin vaccine, disease free equilibrium state, stability and Immunity, , , ,
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Cite this Reference:
A.I. Enagi and M.O. Ibrahim, . Preventing Mother to Child Transmission of Tuberculosis Using Bacillus Calmette-Guérin Vaccine: A Deterministic Modelling Approach. Research Journal of Mathematics and Statistics, (2): 67-71.
ISSN (Online):  2040-7505
ISSN (Print):   2042-2024
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