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Abstract
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Article Information:
Informative Motif Detection Using Data Mining
F.A. Hoque, M. Mohebujjaman and N. Noman
Corresponding Author: Muhammad Mohebujjaman
Submitted: 2010 November, 13
Accepted: 2010 December, 25
Published: 2011 March, 20 |
Abstract:
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Motif finding in biological sequences is a fundamental problem in computational biology with
important applications in understanding gene regulation, protein family identification and determination of
functionally and structurally important identities. The large amounts of biological data let us solve the problem
of discovering patterns in biological sequences computationally. In this research, we have developed an
approach using a method of data mining to detect frequent residue informative motifs that are high in
information content. The proposed approach modifies an existing method based on Apriori algorithm by using
the Frequent Pattern tree (FP-tree) algorithm of data mining method. This method can efficiently detect novel
motifs in biological sequences based on information content of the motifs and shows better performance than
the existing method. Experiments on real biological sequence data sets demonstrate the effectiveness of the
method.
Key words: Data mining, information content, motif, sensitivity, similarity, specificity,
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Abstract
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Cite this Reference:
F.A. Hoque, M. Mohebujjaman and N. Noman, . Informative Motif Detection Using Data Mining. Research Journal of Information Technology , (1): 26-32.
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ISSN (Online): 2041-3114
ISSN (Print): 2041-3106 |
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