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Abstract
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Article Information:
Designing Nonlinear Feedback Control for Controlling Tumor Growth
ArashPourhashemi, Sara Haghighatnia, Reihaneh Kardehi Moghaddam and Nafiseh Mollaei
Corresponding Author: Arash Pourhashemi
Submitted: May 03, 2013
Accepted: June 05, 2013
Published: November 20, 2013 |
Abstract:
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Tumor growth models as nonlinear systems have some equilibrium points. In clinical situations, the
desirable equilibrium point is the state that the competition between the populations of tumor cells and immune cells
tend to the state in which the sizes of these populations do not vary (dormancy mode) or populations of tumor are
zero (free tumor mode). In this study, a feedback nonlinear control for tumor growth model is designed so as to
stabilize the unstable desirable equilibrium points based on Lyapunov stability theory. The aim is to steer the state
trajectories to the desirable equilibrium point in order to treat cancer disease. The efficiency of the proposed method
is shown in the simulation part.
Key words: Equilibrium point, lyapunov stability theory, nonlinear feedback control, tumor growth, , ,
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Cite this Reference:
ArashPourhashemi, Sara Haghighatnia, Reihaneh Kardehi Moghaddam and Nafiseh Mollaei, . Designing Nonlinear Feedback Control for Controlling Tumor Growth. Research Journal of Applied Sciences, Engineering and Technology, (21): 4085-4089.
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ISSN (Online): 2040-7467
ISSN (Print): 2040-7459 |
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