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Abstract
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Article Information:
Formulation and Antimicrobial Studies of Coconut (Cocos nucifera Linne) Oil
A.R. Oyi, J.A. Onaolapo and R.C. Obi
Corresponding Author: Rukayat Oyi
Submitted: 2009 September, 04
Accepted: 2009 September, 24
Published: 2010 March, 10 |
Abstract:
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Coconut oil obtained from the nuts of Cocos nucifera was formulated into creams in order to
standardize its use and present it in an elegant form. Using the fusion method, oil in water (o/w) creams w ere
formulated in concentrations of 5 to 40% w/w of oil.The release of active ingredients from creams was
investigated using cream challenge and skin inoculation tests, whereby creams were exposed to various spots
on skin inoculated with Ps. aeruginosa ATCC 7853, E. coli ATCC 9637, P. vulgaris (clinical isolate),
B. subtilis ATCC 607 and C. albicans ATCC 10231. In addition A. niger (clinical isolate) and S. aureus ATCC
13709 were used for antimicrobial screening.The stability of creams was also evaluated using a standard
method. The results showed that active ingredients of the coconut oil were released from the creams; this was
shown from the good antimicrobial activity of the cream confirming that all formulation ingredients were
compatible and did not interfere with activity of the oil. The creams were also found to be stable, as a result
of their ability to withstand shock and maintain their physical characteristics.
Key words: Antimicrobial, fusion, skin penetration, , , ,
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Cite this Reference:
A.R. Oyi, J.A. Onaolapo and R.C. Obi, . Formulation and Antimicrobial Studies of Coconut (Cocos nucifera Linne) Oil. Research Journal of Applied Sciences, Engineering and Technology, (2): Page No: 133-137.
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ISSN (Online): 2040-7467
ISSN (Print): 2040-7459 |
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