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Abstract
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Article Information:
Methods for DNA Strand Breaks Detection
Gholamreza Motalleb, Nima Sanadgol, Jasem Estakhr and Ebrahim Shahraki
Corresponding Author: Gholamreza Motalleb
Submitted: January 19, 2012
Accepted: March 06, 2012
Published: July 01, 2012 |
Abstract:
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The study of Deoxyribonucleic Acid (DNA) damage holds a wide interest within both basic and
applied fields of research. Elucidating the mechanisms involved in the generation of DNA damage and the
consequences of this damage, will have an enormous impact on multiple fields of scientific research and will
ultimately lead to a better understanding of human disease. In this review article, a variety of experimental
molecular biology techniques will be described.
Key words: DNA strand breaks, flow and laser scanning cytometry, limitations, nick translation and electron microscopy, T4 DNA ligase, TUNEL assay, ultrasound
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Cite this Reference:
Gholamreza Motalleb, Nima Sanadgol, Jasem Estakhr and Ebrahim Shahraki, . Methods for DNA Strand Breaks Detection. Research Journal of Applied Sciences, Engineering and Technology, (13): 1888-1894.
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ISSN (Online): 2040-7467
ISSN (Print): 2040-7459 |
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