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Abstract
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Article Information:
Sequence Analysis of the Protein Structure Homology Modeling of Growth Hormone Gene from Salmo trutta caspius
Abolhasan Rezaei and Sheyda Akhshabi
Corresponding Author: Abolhasan Rezaei
Submitted: 2011 November, 25
Accepted: 2011 Januray, 04
Published: 2012 March, 15 |
Abstract:
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In view of the growth hormone protein investigated and characterized from Salmo trutta caspius.
Growth hormone gene in the Salmo trutta caspius have six exons in the full length that is translated into a
Molecular Weight (kDa): ssDNA: 64.98 and dsDNA: 129.6. There are also 210 amino acid residue. The
assembled full length of DNA contains open reading frame of growth hormone gene that contains 15 sequences
in the full length. The average GC content is 47% and AT content is 53%. This protein multiple alignment has
shown that this peptide is 100% identical to the corresponding homologous protein in the growth hormone
protein which including Salmo salar (Accession number: AAA49558.1) and Rainbow trout (Salmo trutta)
(Accession number: AAA49555.1") sequences. The sequence of protein had deposited in Gene Bank,
Accession number: AEK70940. Also we were analyzed second and third structure between sequences reported
in Gene Bank Network system. The results are shown, there are homology between second structure in three
sequences including: Salmo trutta caspius, Salmo salar and Rainbow trout. Regarding third structure, Salmo
trutta caspius and Salmo salar are same type, but Rainbow trout has different homology with Salmo trutta
caspius and Salmo salar. However, the sequences were observed three parallel " helix and in second structure
there were almost same percent β sheet.
Key words: Growth hormone protein, Salmo trutta caspius, , , , ,
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Cite this Reference:
Abolhasan Rezaei and Sheyda Akhshabi, . Sequence Analysis of the Protein Structure Homology Modeling of Growth Hormone Gene from Salmo trutta caspius. Research Journal of Applied Sciences, Engineering and Technology, (06): 664-669.
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ISSN (Online): 2040-7467
ISSN (Print): 2040-7459 |
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