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2011 (Vol. 3, Issue: 1)
Article Information:

Seroprevalence of Peste des petits ruminants Antibodies in Sheep and Goats after Vaccination in Karamoja, Uganda: Implication on Control

P.D. Luka, J. Erume, F.N. Mwiine and C. Ayebazibwe
Corresponding Author:  Frank Norbert Mwiine 

Key words:  cELISA, control, Karamoja, PPR, sero-conversion, seroprevalence, Uganda, vaccination
Vol. 3 , (1): 18-22
Submitted Accepted Published
2010 October, 20 2010 November, 19 2011 February, 05

A cross sectional survey was carried out to determine the prevalence of antibodies and seroconversion to Peste des petits ruminants virus (PPRV) in small ruminants in Karamoja region, Uganda. This region recently experienced serious outbreaks of PPR prompting vaccination interventions. A total of 316 sera samples (210 of goats and 106 of sheep) were collected from small ruminants with history of vaccination, no vaccination and unknown history in five districts of Karamoja region. Competitive enzyme linked immunosorbent assay (cELISA) was performed to detect the presence of antibodies against PPRV in serum. We found an overall PPRV specific antibody sero-conversion of 55.26% (84/152) (among Vaccinated), seroprevalence of 11.65% (2/17) (in Unvaccinated) and 53.33% (80/150) for shoats with unknown vaccination history. Seropositivity in sheep was 51.89% compared to goats with 57.62%. Among various age groups, 1-2 year olds showed higher sero-positivity (68.57%). Kaabong and Moroto district had highest sero-positivity of animals (78.33%) while Abim district had the lowest sero-positive animals (20%). From this study, it can be concluded that the animals in the region are not fully protected and this is particularly so in districts like Abim. There is need to find out the reasons for the poor protection levels and come up with measures to address these problems in order to improve protection against PPR.
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  Cite this Reference:
P.D. Luka, J. Erume, F.N. Mwiine and C. Ayebazibwe, 2011. Seroprevalence of Peste des petits ruminants Antibodies in Sheep and Goats after Vaccination in Karamoja, Uganda: Implication on Control.  International Journal of Animal and Veterinary Advances, 3(1): 18-22.
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ISSN (Online):  2041-2908
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