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Abstract
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Article Information:
Evaluation of Changes of Factors Related to Liver Function in Serum of Horse by Administration of Cichorium intybus
H. Najafzadeh, A.R. Ghadrdan, M. Jalali and F. Alizadeh
Corresponding Author: Hossein Najafzadeh
Submitted: 2010 February, 20
Accepted: 2010 March, 09
Published: 2011 February, 05 |
Abstract:
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Chicory (Cichorium intybus) is a plant that is cultured in some area of Iran, including Khozestan.
All of parts of the chicory especially its leave and root have medicinal properties. It is traditionally used for
treatment icterus, renal failure, gout and arthritis in human. Important side effects were not reported from this
plant. Excretion substances like uric acid are clinically important in some pathological conditions such as
urecemia and icterus in horse. However the pharmacological effect of chicory was not evaluated in horses. The
present study was conducted for evaluation effect of leave of chicory on changes of factors related to liver
function in serum of horse. In this study, 8 Arabian horses were selected. They had 10-20 years and were
clinically in normal conditions. The horses were fed routine diet. The dried leave of chicory was daily added
to food of horses at 0.5 g/kg for 15 days. The blood of horses was daily collected before, during and 6 days after
chicory administration. The serum was isolated and uric acid, Alanine Transferase (ALT), Aspartate
Transferase (AST), Alkaline Phosphatase (ALP), Lactate Dehydrogenase (LDH), conjugated and total
billirubin, total protein and albumin concentrations were measured. The mean of these factors were statistically
compared. Chicory consumption did not statistically change concentration of above factors. Thus, chicory dose
not affect concentration of ALT, AST, ALP, LDH, conjugated and total billirubin, total protein and albumin
and uric acid in serum of horse in normal condition; but it may be benefit in pathological conditions.
Key words: Albumin, ALP, ALT, AST, billirubin, Cichorium intybus, horse, LDH, total protein, uric acid
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Abstract
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Cite this Reference:
H. Najafzadeh, A.R. Ghadrdan, M. Jalali and F. Alizadeh, . Evaluation of Changes of Factors Related to Liver Function in Serum of Horse by Administration of Cichorium intybus. International Journal of Animal and Veterinary Advances, (1): 1-5.
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ISSN (Online): 2041-2908
ISSN (Print): 2041-2894 |
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