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Abstract
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Article Information:
Small Bowel Wall Response to Enterotomy Closure with Polypropylene and Polyglactin 910 Using Simple Interrupted Suture Pattern in Rats
O.D. Eyarefe and S.A. Amid
Corresponding Author: Eyarefe O. David
Submitted: 2010 April, 19
Accepted: 2010 May, 01
Published: 2010 July, 05 |
Abstract:
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Effects of polypropylene and polyglactin 910 on enterotomy wound healing were investigated.
Sixteen adult W istar albino rats (155.44±30.4 g) w ere randomized into two study groups, A with polypropylene
(n = 8) and B with polyglactin 910 (n = 8) following 1 cm mid-jejunal enterotomy incisions performed under
ketamine/xylazine anaesthesia. Body weights changes were evaluated daily for eleven days and two rats from
each group were euthanized at postoperative days 3, 5, 7 and 11. Following euthanasia, the enterotomy sites
were examined for dehiscence and adhesion. Evidence of inflammatory reactions and fibroblast proliferation
were also evaluated and scored. Leaks from enterotomy site were not observed. Adhesion scores in-group A
(3.5) was statistically significant (p<0.05) when compared with group B (1.875). A non-statistically significant
(p>0.05) but higher fibroblasts count was recorded in Group A (2.625) compared with group B (1.375).
Inflammatory responses in both groups were not statistically significant, although that of Group B was higher
in response than group A. Enterotomy closure with polypropylene produced significant adhesion that may be
linked with the texture of the suture, and the several knots characteristic of the simple interrupted suture pattern.
Key words: Closure, enterotomy, interrupted pattern, polyglactin 910, polypropylene, ,
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Cite this Reference:
O.D. Eyarefe and S.A. Amid, . Small Bowel Wall Response to Enterotomy Closure with Polypropylene and Polyglactin 910 Using Simple Interrupted Suture Pattern in Rats. International Journal of Animal and Veterinary Advances, (3): Page No: 72-75.
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ISSN (Online): 2041-2908
ISSN (Print): 2041-2894 |
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