Home           Contact us           FAQs           
   Journal Page   |   Aims & Scope   |   Author Guideline   |   Editorial Board   |   Search
2010 (Vol. 2, Issue: 3)
Article Information:

Small Bowel Wall Response to Enterotomy Closure with Polypropylene and Polyglactin 910 Using Simple Interrupted Suture Pattern in Rats

O.D. Eyarefe and S.A. Amid
Corresponding Author:  Eyarefe O. David 

Key words:  Closure, enterotomy, interrupted pattern, polyglactin 910, polypropylene, ,
Vol. 2 , (3): Page No: 72-75
Submitted Accepted Published
2010 April, 19 2010 May, 01 2010 July, 05

Effects of polypropylene and polyglactin 910 on enterotomy wound healing were investigated. Sixteen adult W istar albino rats (155.4430.4 g) w ere randomized into two study groups, A with polypropylene (n = 8) and B with polyglactin 910 (n = 8) following 1 cm mid-jejunal enterotomy incisions performed under ketamine/xylazine anaesthesia. Body weights changes were evaluated daily for eleven days and two rats from each group were euthanized at postoperative days 3, 5, 7 and 11. Following euthanasia, the enterotomy sites were examined for dehiscence and adhesion. Evidence of inflammatory reactions and fibroblast proliferation were also evaluated and scored. Leaks from enterotomy site were not observed. Adhesion scores in-group A (3.5) was statistically significant (p<0.05) when compared with group B (1.875). A non-statistically significant (p>0.05) but higher fibroblasts count was recorded in Group A (2.625) compared with group B (1.375). Inflammatory responses in both groups were not statistically significant, although that of Group B was higher in response than group A. Enterotomy closure with polypropylene produced significant adhesion that may be linked with the texture of the suture, and the several knots characteristic of the simple interrupted suture pattern.
Abstract PDF HTML
  Cite this Reference:
O.D. Eyarefe and S.A. Amid, 2010. Small Bowel Wall Response to Enterotomy Closure with Polypropylene and Polyglactin 910 Using Simple Interrupted Suture Pattern in Rats.  International Journal of Animal and Veterinary Advances, 2(3): Page No: 72-75.
    Advertise with us
ISSN (Online):  2041-2908
ISSN (Print):   2041-2894
Submit Manuscript
   Current Information
   Sales & Services
   Contact Information
  Executive Managing Editor
  Email: admin@maxwellsci.com
  Publishing Editor
  Email: support@maxwellsci.com
  Account Manager
  Email: faisalm@maxwellsci.com
  Journal Editor
  Email: admin@maxwellsci.com
  Press Department
  Email: press@maxwellsci.com
Home  |  Contact us  |  About us  |  Privacy Policy
Copyright © 2009. MAXWELL Science Publication, a division of MAXWELLl Scientific Organization. All rights reserved