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Abstract
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Article Information:
Determination of the Hypoglycemic Effect of the Flower of Tamarindus indica on Alloxan Induced Diabetic Mice
Muhammad Yalwa Gwarzo and Hadiza Kabir
Corresponding Author: Muhammad Yalwa Gwarzo
Submitted: July 12,2013
Accepted: September 09, 2013
Published: October 20, 2014 |
Abstract:
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The aim of the study was to examine whether the flower of the plant Tamarind (Tamarindus indica) can prevent alloxan induced diabetes mellitus. The mice were randomly divided into 3 groups of 3 mice each. Diabetes was induced in group 1 and 2 by Intraperitoneal (IP) injection of 180 mg alloxan/kg body weight. Group 1 was induced and treated with 10 mg/kg tamarind. Group 2 was induced (untreated) whereas Group 3 was used as a control (uninduced). Serum Glucose and Malondialdehyde (MDA) levels were determined. Tamarind flowers reduced fasting glucose level and MDA concentration significantly (p<0.05) in induced treated compared with induced untreated without regenerating the b cells. From the result obtained, it can be concluded that, tamarind flower has only hypoglycemic effect with no regeneration of b-cells on chemically induced diabetes.
Key words: Diabetes mellitus, hypoglycaemic effect, oxidative stress, Tamarindus indica, , ,
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Cite this Reference:
Muhammad Yalwa Gwarzo and Hadiza Kabir, . Determination of the Hypoglycemic Effect of the Flower of Tamarindus indica on Alloxan Induced Diabetic Mice. International Journal of Animal and Veterinary Advances, (5): 139-142.
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ISSN (Online): 2041-2908
ISSN (Print): 2041-2894 |
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