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2012 (Vol. 4, Issue: 3)
Article Information:

Biotoxic and Haemotoxic Effects of Air Pollutants at a Benzene Station on Albino Rats

M. Abousalem, A. Elgerwi and A. El-Mashad
Corresponding Author:  M. Abousalem 

Key words:  Benzene, blood, kidney, liver, pollutants, toxic,
Vol. 4 , (3): 187-190
Submitted Accepted Published
March 23, 2012 April 10, 2012 June 15, 2012

This study was directed to explore the hazardous effect of occupational exposure to air pollutants arised from benzene station. A total of 48 albino rats were calssified into three groups each of sixteen rats. Groups one and two were kept at a benzene station for 60 and 120 days, respectively and the third group was kept as a control under laboratory conditions. After termination of the experiment, animals were sacrificed and blood samples were collected for hematological and biochemical investigations. Sera were separated and used to check the effects of air pollutants arising at a benzene station on the liver and kidney functions as well as on the immune status of the body. Results indicated a pronounced time-dependent reductions in RBCs, Hb, PCV, total and differential (neutrophil and lymphocyte) leucocytic counts. Total protein, albumin, globulin and immunoglobulins IgG, IgA and IgM showed marked lower levels in animals exposed to air pollutants in the benzene station. Organ function tests revealed elevations of the levels of AST, ALT, ALP and GGT that indicate impaired liver function compared to those of the corresponding control. Similar results were recorded for creatinine kinase, urea and creatinine indicating toxic effects on the heart and kidneys.
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  Cite this Reference:
M. Abousalem, A. Elgerwi and A. El-Mashad, 2012. Biotoxic and Haemotoxic Effects of Air Pollutants at a Benzene Station on Albino Rats.  International Journal of Animal and Veterinary Advances, 4(3): 187-190.
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ISSN (Online):  2041-2908
ISSN (Print):   2041-2894
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