Home           Contact us           FAQs           
 
   Journal Page   |   Aims & Scope   |   Author Guideline   |   Editorial Board   |   Search
    Abstract
2012 (Vol. 4, Issue: 5)
Article Information:

Effect of Nano-Particle of Magnesium Oxide on Ketamine-Induced Anesthesia in Rabbit

N. Kavosi, H. Najafzadeh, M. Bavari and A. Esmailirad
Corresponding Author:  H. Najafzadeh 

Key words:  Anesthesia, ketamine, mgo nano-particles, rabbit, , ,
Vol. 4 , (5): 592-595
Submitted Accepted Published
June 07, 2012 June 23, 2012 September 20, 2012
Abstract:

Some studies show magnesium has analgesic effect in some pain models but this evaluation was not carried on nano-Magnesium Oxide (MgO). Thus, present study was designed to evaluation effect of Mgo nanoparticles and conventional MgO on ketamine-induced anesthesia in rabbits. At this study, 20 adult rabbits were used in 4 groups. Ketamine was intrapritonealy injected in all groups and xylazine, MgO nanoparticle and MgO suspension was administrated 15 min before ketamine injection in 3 last groups. The rectal temperature, respiratory rate and heart rate were measured before drug administration and during of anesthesia. Duration of anesthesia and recovery time was recorded. The mean of body temperature and heart rate changed in groups but this change was not significant except group1 which received only ketamine. The mean of respiratory rate significantly decreased before and after anesthesia in all groups but this decreasing was greater (nearly 3 fold) in group 2 which received ketemine and xylazine. Also duration of anesthesia was longer significantly in this group. Thus quality and duration of ketamine-induced anesthesia did not differ by MgO-nanoparticles with comparison to conventional Mg-O.
Abstract PDF HTML
  Cite this Reference:
N. Kavosi, H. Najafzadeh, M. Bavari and A. Esmailirad, 2012. Effect of Nano-Particle of Magnesium Oxide on Ketamine-Induced Anesthesia in Rabbit.  Current Research Journal of Biological Sciences, 4(5): 592-595.
    Advertise with us
 
ISSN (Online):  2041-0778
ISSN (Print):   2041-076X
Submit Manuscript
   Current Information
   Sales & Services
   Contact Information
  Executive Managing Editor
  Email: admin@maxwellsci.com
  Publishing Editor
  Email: support@maxwellsci.com
  Account Manager
  Email: faisalm@maxwellsci.com
  Journal Editor
  Email: admin@maxwellsci.com
  Press Department
  Email: press@maxwellsci.com
Home  |  Contact us  |  About us  |  Privacy Policy
Copyright © 2009. MAXWELL Science Publication, a division of MAXWELLl Scientific Organization. All rights reserved