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2012 (Vol. 4, Issue: 3)
Article Information:

Correlation of Optic Neuritis with Multiple Sclerosis and Evaluating the Response of Optic Neuritis Treatment of Hospitalized Patients with Ophthalmologic Complaints in Imam and Motahari Hospitals of Urmia, Northwest Iran

Qader Motarjemizadeh, Naser Samadi Aydenloo, Peyman Mikaili and Mohsen Ghajavand
Corresponding Author:  Peyman Mikaili 

Key words:  Iran, MRI, multiple sclerosis, optic neuritis, urmia, visual evoked potential,
Vol. 4 , (3): 279-283
Submitted Accepted Published
December 23, 2011 February 09, 2012 April 05, 2012
Abstract:

The aim of this study was to determine the frequency rate of optic neuritis among patients with ocular symptoms, hospitalized at Imam and Motahari Hospitals and evaluating the causes and factors contributing to this disease and the extent of treatment response. It usually occurs as acute or subacute. Although there is no definitive cause in most of the time and considered as idiopathic, but in some cases, especially between young females, Optic Neuritis could be a sign for beginning of multiple sclerosis. We enrolled all cases that hospitalized as optic neuritis in Imam and Motahari Hospital in a retrospective crosssectional study. Data about the Visual Acuity in the 1st, 3rd and 10th days of hospitalization and also the results of Visual Evoked Potential (VEP) and MRI were collected and analyzed in SPSS software version 16. Thirty two cases enrolled in the study with minimum age of 9 and maximum age of 57 years old (mean age = 32 years). 66% were female. Eleven cases (34.4%) has Hand Motion (HM) visual acuity, 12.5% has 0.5 m Finger Count (FC), 21.9% has 1 m FC, 9.4% has 2 m FC, 6.2% has 3 m FC, and finally 1 cases (3.1%) has each degrees of visual acuity as following 4, 5 and 6 m FC, 1, 2 and 3/10, respectively. Ten days after treatment, 6 cases has 8/10, 18 cases (50%) has 9/10, and 10 cases has complete visual acuity. Only in 11 cases (33%), MRI has a kind of evidence compatible with optic neuritis. VEP in 87% of cases were suggestive for optic neuritis. Lower rate of abnormal MRI results in this study could reveals early imaging with MRI. MRI after first week and through 6 months after ON could show the plaques more. VEP has more sensitivity and MRI has more specificity in diagnosing Optic Neuritis.
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  Cite this Reference:
Qader Motarjemizadeh, Naser Samadi Aydenloo, Peyman Mikaili and Mohsen Ghajavand, 2012. Correlation of Optic Neuritis with Multiple Sclerosis and Evaluating the Response of Optic Neuritis Treatment of Hospitalized Patients with Ophthalmologic Complaints in Imam and Motahari Hospitals of Urmia, Northwest Iran.  Current Research Journal of Biological Sciences, 4(3): 279-283.
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ISSN (Online):  2041-0778
ISSN (Print):   2041-076X
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