|
Abstract
|
Article Information:
Expression Analysis of CAMP-Responsive Element Modulator Mrna in Different Tissues of Goat
Nasim Javdan and Jasem Estakhr
Corresponding Author: Jasem Estakhr
Submitted: 2011 September, 21
Accepted: 2011 October, 24
Published: 2012 January, 20 |
Abstract:
|
CAMP-Responsive Element Modulator (CREM) is a key factor in the regulation of the expression
of number of post-meiotic genes during spermatogenesis. CREM binds to transcription factor and regulates
gene expression in spermatids. In the present study tissue-specific expressions of CREM and different
development stage expressions of CREM in testes of goat were quantified using qRT-PCR. The highest level
was detected in testes (p<0.05). The expression of CREM mRNA reached the highest level in 20-wk-old testes
(p<0.05). Furthermore, immunohistochemistry localized CREM mainly expressed in round spermatids, but not
in spermatogonium and spermatocyte. These results indicated that CREM was a regulation proteins and it may
play an important role in spermatid maturation.
Key words: CAMP-responsive element modulator, gene expression, goat, QRT-PCR, , ,
|
|
Abstract
|
PDF
|
HTML |
|
Cite this Reference:
Nasim Javdan and Jasem Estakhr, . Expression Analysis of CAMP-Responsive Element Modulator Mrna in Different Tissues of Goat. Current Research Journal of Biological Sciences, (1): 27-32.
|
|
|
|
 |
ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
 |
| Information |
|
|
|
|
| Sales & Services |
|
|
|
|
