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Abstract
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Article Information:
Screening Response to Hepatitis C Virus Antibodies among Diabetic Patients Attending UITH Nigeria
J.A. Ndako, O.O. Nwankiti, C.O. Okeke, A.M. Adekeye, T.P. Choji, M.U. Alesa and A.J. Alarape
Corresponding Author: JAMES A. NDAKO
Submitted: 2011 February, 20
Accepted: 2011 April, 20
Published: 2011 November, 15 |
Abstract:
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Epidemiological studies have suggested that hepatitis C virus (HCV) infection is a risk factor for the
development of diabetes mellitus (DM) type 2; hence this study was carried out to investigate the prevalence
of hepatitis C Virus (HCV) among diabetic patients attending University of Ilorin Teaching Hospital (UITH).
A total number of one hundred and eighty diabetic patients made up of seventy five males (41.7%) and one
hundred and five females (58.3%) were recruited for the study. Structured questionnaire on demographic data
and risk factors for HCV was administered to the participants. The sera of all the subjects were assayed for
antibodies to HCV using a fourth generation enzyme linked immunosorbent Assay [Forte Diagnostic Limited],
All the sera were tested for antibodies to Hepatitis C virus by ELISA method. The overall prevalence of HCV
infection among diabetic patients was 5.0%. Of the nine participants’ positive for anti-HCV antibodies, three
were males (1.7%) while six were females (3.3%). Although more female attended the diabetic clinic, there was
no significant difference between HCV infection and sex (p = 0.603; p>0.05). The prevalence of HCV infection
was highest in the 40-60 age categories. Two of the seropositive individuals had elevated transaminases, with
one of the two being an alcoholic consumer. Type 2 diabetes is a debilitating disease condition especially in
individuals above 30 years of age, with these scenario it has become very vital for screening exercise to be
carried out so as to determine the prevalence rate of HCV among diabetic patient.
Key words: Antibodies, hepatitis c virus, type 2 diabetics, , , ,
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Cite this Reference:
J.A. Ndako, O.O. Nwankiti, C.O. Okeke, A.M. Adekeye, T.P. Choji, M.U. Alesa and A.J. Alarape, . Screening Response to Hepatitis C Virus Antibodies among Diabetic Patients Attending UITH Nigeria. Current Research Journal of Biological Sciences, (6): 542-546.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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