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Article Information:
Evaluation of Hypoglycemic and Antioxidative Properties of Aqueous Extract of Garcinia kola Seeds in Wistar Rats
Omage Kingsley, Erifeta O. Georgina, Uhunmwangho S. Esosa, Josiah J. Sunday and Ajeigbe O. Kazeem
Corresponding Author: Omage Kingsley
Submitted: 2011 March, 09
Accepted: 2011 April, 16
Published: 2011 April, 15 |
Abstract:
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The effects of aqueous extract of Garcinia kola seed on glucose, superoxide dismutase catalase and
malondialdehyde of normal rats were investigated. Oral administration of aqueous seed extract of Garcinia kola
at a concentration of 200 mg/kg body weight, over a period of 21 days, significantly (p<0.05) decreased the
levels of blood glucose, increased the activity of superoxide dismutase (p<0.05), and that of malondialdehyde
(p<0.05). Our treatment however, had no significant effect (p>0.05) on the activity of catalase. The elicitation
of these effects by the plant is a reflection of its hypoglycemic and antioxidative properties.
Key words: Aqueous extract, catalase, Garcinia kola seeds, lipid peroxidation, MDA, SOD,
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Cite this Reference:
Omage Kingsley, Erifeta O. Georgina, Uhunmwangho S. Esosa, Josiah J. Sunday and Ajeigbe O. Kazeem, . Evaluation of Hypoglycemic and Antioxidative Properties of Aqueous Extract of Garcinia kola Seeds in Wistar Rats. Current Research Journal of Biological Sciences, (4): 326-329.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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