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    Abstract
2014 (Vol. 5, Issue: 2)
Article Information:

Probiotic Efficacy of Lactobacillus reuteri Culture Filtrates against Certain Groups of Proliferating Bacteria Isolated from Acne Abscess

Saud H. Al Motuirei and A.M.A. Saadabi
Corresponding Author:  A.M.A. Saadabi 

Key words:  Acne, culture filtrates, kingdom of Saudi Arabia, Lactobacillus reuteri, probiotics, ,
Vol. 5 , (2): 98-102
Submitted Accepted Published
January 23, 2014 February 15, 2014 April 20, 2014
Abstract:

Acne is a common disease in Saudi nationals particularly among adolescents and young adults. The disease has substantial effects on quality of life which making treatment essential. Probiotics nowadays is becoming a method of first choice to combat the disease. The present study was carried out to evaluate and to identify the causative agents of acne disease in Shaqra region. Subsequently, the effects of culture filtrate of the bacterium Lactobacillus reuteri on the in vitro growth of bacterial isolates obtained from acne i.e., Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acnes and Propionibacterium granulosum were also carried out along with the subsequent inhibitory impacts on acne symptomatology. It was observed that the culture filtrates of L. reuteri were significantly inhibitory to the growth of the four bacterial species. Increase in zone of inhibition was directly correlated with concentration of L. reuteri. L. reuteri at both diluted and concentrated doses was inhibitory at 24, 48 and 72 h of incubation periods. The most inhibitory incubation period was 48 h using well-diffusion agar technique with concentrated filtrate. The toxicity of the culture filtrate was largely influenced by the dilution and incubation period. Antibiotics sensitivity tests against different bacterial isolates was tested using Triclosan, Benzoyl peroxidase, Erythromycin, Retinoid, Tetracycline and Clindamycin. All of the bacterial isolates were vulnerable (susceptible, sensitive) to Triclosan and Benzoyl peroxidase, Retinoid, Tetracycline and Clindamycin, but all of the isolates were resistant to Erythromycin antibiotic. It could be concluded that the culture filtrate of L. reuteri could be used as probiotics and a source of biological control agents to cure acne disease in the area.
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  Cite this Reference:
Saud H. Al Motuirei and A.M.A. Saadabi, 2014. Probiotic Efficacy of Lactobacillus reuteri Culture Filtrates against Certain Groups of Proliferating Bacteria Isolated from Acne Abscess.  British Journal of Pharmacology and Toxicology, 5(2): 98-102.
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ISSN (Online):  2044-2467
ISSN (Print):   2044-2459
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