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    Abstract
2013 (Vol. 4, Issue: 3)
Article Information:

Anti-hyperglycemic Properties of Moringa oleiferaLam. Aqueous Leaf Extract in Normal and Mildly Diabetic Mice

Ampa Luangpiom, Watchara Kourjampa and Tanaree Junaimaung
Corresponding Author:  Ampa Luangpiom 

Key words:  Diabetes, glibenclamide, glucose tolerance, Moringa oleifera Lam., , OGTT, stretozotocin,
Vol. 4 , (3): 106-109
Submitted Accepted Published
January 12, 2013 February 07, 2013 June 25, 2013
Abstract:

Aqueous leaves extract of Moringa oleifera Lam. was studied for its anti-hyperglycemic properties in normal and mildly diabetic mice by the Oral Glucose Tolerance Test (OGTT). The glibenclamide (1 mg/100 g BW) was used as reference drug. And mildly diabetes was induced by a single intraperitoneal injection of sterptozotocin (6 mg/100 g BW). The blood glucose tolerance efficiency of the extract at doses of 100, 200 and 300 mg/100 g BW in normal group were 25.99, 31.25 and 43.19% and in mildly diabetic mice were 45.17, 53.31 and 59.16% of glibenclamide, respectively. In conclusion, the aqueous leaves extract of Moringa oleifera Lam. revealed anti-hyperglecemic activity in normal mice and improved the glucose tolerance impairment in mildly diabetic mice. Thus, Moringa oleifera Lam may be introduced as an anti-diabetic herb.
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  Cite this Reference:
Ampa Luangpiom, Watchara Kourjampa and Tanaree Junaimaung, 2013. Anti-hyperglycemic Properties of Moringa oleiferaLam. Aqueous Leaf Extract in Normal and Mildly Diabetic Mice .  British Journal of Pharmacology and Toxicology, 4(3): 106-109.
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ISSN (Online):  2044-2467
ISSN (Print):   2044-2459
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