Home           Contact us           FAQs           
 
   Journal Page   |   Aims & Scope   |   Author Guideline   |   Editorial Board   |   Search
    Abstract
2012 (Vol. 3, Issue: 2)
Article Information:

Antibiotic Resistance and Plasmid Profiling of Clinically Significant Vibrio vulnificus Isolated from Coastal Water in Eastern Province of Saudi Arabia

Nasreldin Elhadi
Corresponding Author:  Nasreldin Elhadi 

Key words:  Antibiotic resistance, coastal water, plasmid DNA, Vibrio vulnificus, , ,
Vol. 3 , (2): 93-97
Submitted Accepted Published
March 06, 2012 March 30, 2012 April 25, 2012
Abstract:

Vibrio vulnificus is an estuarine bacterium that is capable of causing a rapidly fatal infection in humans. The aim of this study to investigate the occurrence, antibiotic resistance and plasmid profiles of V. vulnificus in Eastern Province of Saudi Arabia coastal water. A total of 10 isolates of V. vulnificus isolated from coastal water of Arabian Gulf in Eastern Province of Saudi Arabia. All isolates showed a multiple resistance towards all 10 antibiotics tested. Some of the isolates showed a high resistance to different antibiotics including gentamicin, ticarcillin, cefaclor, amikacin, augmentin and ampicillin. However, all isolates of V. vulnificus was susceptible to tetracycline and ampicillin. Overall antibiotics resistance patterns of all isolates were resistant from 2 to 3 patterns with Multiple Antibiotic Resistance (MAR) index ranging from 0.2 to 0.5 respectively. 4 out of 10 isolates of V. vulnificus harbored plasmid DNA with size ranging from 3.7 to 4.9 kb. These findings are very important because of the involvement of seawater in transmission of this pathogen to human. V. vulnificus is responsible of causing severe wound infection and is often characterized by necrotizing skin and soft-tissue infection, primary sepsis in certain high-risk populations, including patients with chronic liver disease, immunodeficiency, iron storage disorders, end-stage renal disease and diabetes mellitus.
Abstract PDF HTML
  Cite this Reference:
Nasreldin Elhadi, 2012. Antibiotic Resistance and Plasmid Profiling of Clinically Significant Vibrio vulnificus Isolated from Coastal Water in Eastern Province of Saudi Arabia.  British Journal of Pharmacology and Toxicology, 3(2): 93-97.
    Advertise with us
 
ISSN (Online):  2044-2467
ISSN (Print):   2044-2459
Submit Manuscript
   Current Information
   Sales & Services
   Contact Information
  Executive Managing Editor
  Email: admin@maxwellsci.com
  Publishing Editor
  Email: support@maxwellsci.com
  Account Manager
  Email: faisalm@maxwellsci.com
  Journal Editor
  Email: admin@maxwellsci.com
  Press Department
  Email: press@maxwellsci.com
Home  |  Contact us  |  About us  |  Privacy Policy
Copyright © 2009. MAXWELL Science Publication, a division of MAXWELLl Scientific Organization. All rights reserved