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2011 (Vol. 2, Issue: 5)
Article Information:

Isolation of Steroids from Acetone Extract of Ficus iteophylla

I.A. Abdulmalik, M.I. Sule, A.M. Musa, A.H. Yaro, M.I. Abdullahi, M.F. Abdulkadir and H. Yusuf
Corresponding Author:  Abdulmalik Ismail 

Key words:  Ficus iteophylla, 1: H- NMR, 13: C- NMR, DEPT, 3β-cholest-5-ene-3, 23diol, 24 ethyl cholest-5-ene-3β-ol
Vol. 2 , (5): 270-272
Submitted Accepted Published
2011 September, 08 2011 September, 30 2011 November, 25
Abstract:

Two steroids were isolated from the leaves of Ficus iteophylla (Family: moraceae) a plant popularly used in African traditional medicine to treat variety of illnesses. The leaf part of the plant was investigated phytochemically using a standard procedure. Schematic fractionation of its ethanol extract by acetone and methanol and subsequent column chromatography of the acetone fraction over silica gel G (60-120) mesh size led to the isolation of 3β-cholest-5-ene-3, 23diol (1) and 24 ethyl cholest-5-ene- 3β-ol (2). The structure of these two compounds was elucidated using 1H-NMR, 13C- NMR and DEPT analysis. To the best of our search this is the first report on the isolation of these compounds from the leaves of Ficus iteophylla.
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  Cite this Reference:
I.A. Abdulmalik, M.I. Sule, A.M. Musa, A.H. Yaro, M.I. Abdullahi, M.F. Abdulkadir and H. Yusuf, 2011. Isolation of Steroids from Acetone Extract of Ficus iteophylla.  British Journal of Pharmacology and Toxicology, 2(5): 270-272.
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