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2011 (Vol. 2, Issue: 4)
Article Information:

Effects of Aqueous Root Extract of Treculia africana on Glucose, Serum Enzymes and Body Weight of Normal Rabbits

Omage Kingsley, Onoagbe O. Iyere and Erifeta O. Georgina
Corresponding Author:  Omage Kingsley 

Key words:  ALT, AST, hepatoprotective, hypoglycemic, LDH, Treculia africana, weight gain
Vol. 2 , (4): 159-162
Submitted Accepted Published
2011 April, 27 2011 June, 10 2011 October, 25
Abstract:

The present study was undertaken to investigate the effect of aqueous root extract of Treculia africana on blood glucose levels, AST, ALT, and LDH activities, as well as body weight of normal rabbits. Oral administration of aqueous root extract of Treculia africana at a dose of 200 mg/kg body weight, for a period of 21 days, caused a significant (p<0.05) reduction in glucose concentration and AST activity, and a slight decrease in ALT activity. The treatment also showed no significant (p>0.05) effect on LDH activity and a slight increase in body weight of the test animals. These effects of the plant are a reflection of its hypoglycemic and hepatoprotective properties, as well as its relative safety and possible use for weight gain.
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  Cite this Reference:
Omage Kingsley, Onoagbe O. Iyere and Erifeta O. Georgina, 2011. Effects of Aqueous Root Extract of Treculia africana on Glucose, Serum Enzymes and Body Weight of Normal Rabbits.  British Journal of Pharmacology and Toxicology, 2(4): 159-162.
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