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Abstract
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Article Information:
Effect of Aqueous Kola Nut (Cola nitida rubra) Extract on Sperm Quality in Male Spraque – Dawley Rats
W.A. Adisa, B.O. Iranloye, C.C. Ezekunie, A.O. Nwaopara, C.U. Osifoh, E.N.S. Igbinovia and H.O. Otamere
Corresponding Author: Nwaopara, Anthony Obioma
Submitted: 2010 January, 20
Accepted: 2010 February, 11
Published: 2010 March, 15 |
Abstract:
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This study evaluated the effects of kola nut extract on sperm quality in male Sprague dawley rats.
30 adult male rats were used. These were divided into three groups: group A served as control, groups B and
C received kola nut extract only (8mg/kg body weight), C served as recovery group. All the groups were treated
for four weeks. Group C, which served as recovery group, was allowed to recover for another four weeks after
the extract administration. Parameters of sperm quality: count, morphology and motility w ere insignificantly
decreased. However, life/dead ratio was significantly decreased (p<0.05). The recovery group showed values
that were insignificantly decreased but a bit closer to those of the control animals. This showed that the rats
were able to recover to some extent after the extract administration. This indicates that consumption of cola nut
has little, if any impact on semen quality.
Key words: Kola nut extract, caffeine, sperm quality, semen, sprague dawley rat, Cola nitida,
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Cite this Reference:
W.A. Adisa, B.O. Iranloye, C.C. Ezekunie, A.O. Nwaopara, C.U. Osifoh, E.N.S. Igbinovia and H.O. Otamere, . Effect of Aqueous Kola Nut (Cola nitida rubra) Extract on Sperm Quality in Male Spraque – Dawley Rats. Asian Journal of Medical Sciences, (2): Page No: 77-80.
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ISSN (Online): 2040-8773
ISSN (Print): 2040-8765 |
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