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     Asian Journal of Medical Sciences

    Abstract
2013(Vol.5, Issue:2)
Article Information:

Total Antioxidant Capacity (Tac) in Hypertensive Patients

S.C. Onuoha, U.E. Uzuegbu and Apu Murphy
Corresponding Author:  S.C. Onuoha 
Submitted: July 17, 2012
Accepted: October 22, 2012
Published: April 25, 2013
Abstract:
Hypertension has been an age long ailment that has affected the entire population of the world with its many complications. This study investigated the relationship between hypertension and TAC in different age groups. Samples were collected from Bomadi general hospital in Bomadi Local Government Area of Delta State, Nigeria and the project was also conducted there. A total of 40 consenting subject between the age of 45-65 years were randomly selected for the study of which 20 were control subjects (non-hypertensive individuals). The age groups 40-49 years in hypertensive patients and 60-69 years in normotensive individuals indicate statistical significance when compared to their corresponding age group (0.9±0.25mMol/L and 1.68±0.32Mmol/L, respectively). In hypertensive subject, male shows a statistically insignificant (p≤0.05) mean higher value than female (1.14±0.18Mmol/L) and 1.01±0.21Mmol/l, respectively) while in normotensive subjects, female shows a statistically significant (p≤0.05) mean lower value than male (1.66±0.35mMol and 1.77±0.06, respectively). Total antioxidant capacity is lower in hypertensive patients and as a result these individuals are predisposed to ills associated with reduced TAC. This includes cell damage by free radicals.

Key words:  Antioxidant capacity, hypertensive patients, normotensive, , , ,
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Cite this Reference:
S.C. Onuoha, U.E. Uzuegbu and Apu Murphy, . Total Antioxidant Capacity (Tac) in Hypertensive Patients. Asian Journal of Medical Sciences, (2): 37-40.
ISSN (Online):  2040-8773
ISSN (Print):   2040-8765
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