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Abstract
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Article Information:
In vitro Antimicrobial Assessment of Lepidium sativum L. Seeds Extracts
Shama I.Y. Adam, Shayma A.M. Salih and Warda S. Abdelgadir
Corresponding Author: Warda S. Abdelgadir
Submitted: 2011 October, 23
Accepted: 2011 November, 25
Published: 2011 December, 25 |
Abstract:
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The antimicrobial activity of the petroleum ether, methanol and water extracts of Lepidium sativum
seed extracts against six opportunistic pathogens namely Staphylococcus aureus, Escherichia coli, Klebsiella
pneumonae, Proteus vulgaris, Pseudomonas aeruginosa and one fungus Candida albicans was assessed using
the concentrations of 2.5, 5 and 10%. The antimicrobial activity of plant seeds extracts were compared with
that of Gentamicin or Ketoconzol, as reference antibiotics. The petroleum ether extract of Lepidium sativum
seeds in different concentrations (2.5-5-10%) were found to be active antimicrobials against all the test
microorganisms with a strong antifungal activity at the concentration 2.5 and 10%. At the concentration of 5%,
the methanolic extract of this plant had no activity against Candida albicans. Staphylococcus aureus and
Candida albicans were resistant to 2.5 and 5% water extracts, whereas the latter was also resistant to 5%
methanolic extract. The antimicrobial activity of Gentamicin and Ketoconzol against the same test
microorganisms was compared with that of the extracts of L. sativum seeds.
Key words: Antimicrobial activity, C. albicans, E. coli, K. pneumonae, Lepidium sativum, P. vulgaris, P. aeruginosa, S. aureus
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Abstract
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Cite this Reference:
Shama I.Y. Adam, Shayma A.M. Salih and Warda S. Abdelgadir, . In vitro Antimicrobial Assessment of Lepidium sativum L. Seeds Extracts. Asian Journal of Medical Sciences, (6): 261-266.
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ISSN (Online): 2040-8773
ISSN (Print): 2040-8765 |
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