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Abstract
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Article Information:
Evaluation of Some Risk Factors for Atherosclerosis in the Circle of Willis Observed at Autopsy in University Collegehospital, Ibadan, Nigeria
J. Olusakin, A.D.T. Goji, I. Ezekiel, O.O. Oladipo, G.O. Ogun, S.S. Dare, S.B.Mesole and Y.G. Mohammed
Corresponding Author: Ezekiel Iliya
Submitted: 2011 June, 04
Accepted: 2011 August, 05
Published: 2011 October, 25 |
Abstract:
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There has been a steady change in lifestyle of the Nigerians causing the increase in vulnerability of
cerebrovascular disease like atherosclerosis. This study was aimed at evaluating some risk factors for
atherosclerosis in the circle of Willis autopsy. The clinical record of patients were retrieved from their case files
in order to obtain information on the sex, age, clinical diagnosis, past medical history and presence or absence
of cardiovascular risk factors such as cigarette smoking, alcohol intake, diabetes, and hypertension. Samples
were obtained from 44 consecutive brains in autopsies conducted on subjects aged 15 years and above at the
University College Hospital, Ibadan. With ethical clearance, the subject’s case files were retrieved for some
data. Twenty-six (59.1%) of the subjects had no identifiable risk factors for atherosclerosis in their medical
history. Eighteen (40.9%) of the subjects had at least one risk factor of atherosclerosis in their history. The risk
factors identified were hypertension in 10 (55.6%) cases, hypertension combined with previous alcohol
ingestion in 3 (16.7%) cases, hypertension combined with diabetes mellitus in 3 (16.7%) cases, and alcohol
ingestion in 2 (11.1%) cases (Thus, a total of 16 (61.5%) patients had hypertension, 6 (33.3%) patients had a
history of alcohol ingestion.
Key words: Atherosclerosis, autopsy, cerebrovascular, circle of willis, diabetes mellitus, hypertension,
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Cite this Reference:
J. Olusakin, A.D.T. Goji, I. Ezekiel, O.O. Oladipo, G.O. Ogun, S.S. Dare, S.B.Mesole and Y.G. Mohammed, . Evaluation of Some Risk Factors for Atherosclerosis in the Circle of Willis Observed at Autopsy in University Collegehospital, Ibadan, Nigeria. Asian Journal of Medical Sciences, (5): 186-191.
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ISSN (Online): 2040-8773
ISSN (Print): 2040-8765 |
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