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Abstract
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Article Information:
Antioxidant and Antitumor Effect of Different Fractions of Ethyl Acetate Part from Elaeagnus angustifolia L.
Wang Ya, Zhou Shang-Zhen, Zhao Chun-Meng, Guo Tao, Ma Jian-Ping, Zhao Ping and Ran Qiu-xiu
Corresponding Author: Guo Tao
Submitted: February 28, 2014
Accepted: April 17, 2014
Published: May 10, 2014 |
Abstract:
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To determine antitumor and antioxidant activities of the different fractions of ethyl acetate of Elaeagnus angustifolia L. extract, the MTT assay, the DPPH scavenging assay and the reducing power method were used. The results showed that as the concentration and the polarity were increasing, the antioxidant activity of the different fractions of ethyl acetate of Elaeagnus angustifolia L. extract was increased. The DPPH scavenging of the E and F fractions was 94.9%. The antitumor assay showed that the different fractions of ethyl acetate of Elaeagnus angustifolia L. exhibited the inhibition of the in vitro cultured Hela cell proliferation properties. During the first 48 h, there was a dependant relation of inhibition effect and the concentration and the polarity. The higher the concentration and the polarity, the stronger the inhibition effect was. The inhibition rate was 74.34% when the concentration of F faction was 2.5 mg/mL.
Key words: Antioxidant, antitumor activities, different fractions, DPPH, Elaeagnus angustifolia L., ethyl acetate part, reducing power,
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Cite this Reference:
Wang Ya, Zhou Shang-Zhen, Zhao Chun-Meng, Guo Tao, Ma Jian-Ping, Zhao Ping and Ran Qiu-xiu, . Antioxidant and Antitumor Effect of Different Fractions of Ethyl Acetate Part from Elaeagnus angustifolia L.. Advance Journal of Food Science and Technology, (5): 707-710.
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ISSN (Online): 2042-4876
ISSN (Print): 2042-4868 |
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