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2014 (Vol. 6, Issue: 2)
Article Information:

Effect of Consumption of Coleus tuberosus on the Lipid Profile of Alloxan-induced Diabetic Rats

Mutiara Nugraheni, Umar Santoso and Windarwati
Corresponding Author:  Mutiara Nugraheni 

Key words:  C. tuberosus , diabetes mellitus, lipid profile, resistant starch, , ,
Vol. 6 , (2): 159-166
Submitted Accepted Published
July 28, 2013 August 06, 2013 February 10, 2014
Abstract:

Coleus tuberosus is a minor vegetable belonging to the Lamiaceae family. C. tuberosus and processed products have been evaluated on resistant starch content and effect of consumption of C. tuberosus and processed products on the lipid profile has been studied in rats with diabetes mellitus. Resistant starch was analyzed using the megazyme method. Analysis of lipid profile was performed in experimental alloxan-induced animals. Such lipid profile as Total Cholesterol (TC), Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL) are determined enzymatically by the Cholesterol Oxidase-oxidase-Phenol Aminophenazone (CHOD-PAP) method. Triglyceride levels are determined by the enzymatic Glycerol-3-Phosphate Oxidase-Phenol+Aminophenazone (GPO-PAP) method. The results showed that the treatment process can increase the levels of resistant starch. C. tuberosus consumption and processed products can lower the lipid profile of TC, TG and LDL and increase HDL in experimental animals. Resistant starch contained in C. tuberosus and processed products is one of the factors that affect the lipid profile of experimental animals with diabetes mellitus.
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  Cite this Reference:
Mutiara Nugraheni, Umar Santoso and Windarwati, 2014. Effect of Consumption of Coleus tuberosus on the Lipid Profile of Alloxan-induced Diabetic Rats.  Advance Journal of Food Science and Technology, 6(2): 159-166.
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