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    Abstract
2012 (Vol. 4, Issue: 2)
Article Information:

Bioactivities and Iridoid Determination of a Beverage Containing Noni, Cornelian Cherries and Olive Leaf Extract

Brett J. West, De-lu Ma, Shixin Deng, C. Jarakae Jensen and Chen X. Su
Corresponding Author:  Brett J. West 

Key words:  Advanced glycation end products, antioxidant, cornelian cherries, iridoids, noni, olive leaf extract,
Vol. 4 , (2): 91-96
Submitted Accepted Published
January 21, 2012 February 08, 2012 April 20, 2012
Abstract:

The aim of the current study was to evaluate the iridoid content, as well as the in vitro and in vivo bioactivities, of a beverage containing noni fruit, Cornelian cherries, and olive leaf extract (Thrive Adaptogenics Max). The average total iridoid content of the beverage was 2.09 mg/mL. The major iridoids present were identified as asperulosidic acid, deacetylasperulosidic acid, oleuropein, morroniside, loganic acid, and loganin. In the 2, 2-Diphenylpicrylhydrazyl (DPPH) radical scavenging assay, remarkably high in vitro antioxidant activity was observed, with an IC50 of 3.8 :L/mL. In vivo bioactivities were evaluated in type 2 diabetic Sprague Dawley rats. In a dose-dependent manner, Thrive Adaptogenics Max reduced abnormal weight gain, blood glucose levels, and serum Advanced Glycation End products (AGEs), as well as improved immunity via increased T cell counts and CD4+/CD8+ ratios. These results suggest that this blend of ingredients is beneficial for improving and maintaining health in the general population, as well as among those with metabolic imbalance.
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  Cite this Reference:
Brett J. West, De-lu Ma, Shixin Deng, C. Jarakae Jensen and Chen X. Su, 2012. Bioactivities and Iridoid Determination of a Beverage Containing Noni, Cornelian Cherries and Olive Leaf Extract.  Advance Journal of Food Science and Technology, 4(2): 91-96.
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ISSN (Online):  2042-4876
ISSN (Print):   2042-4868
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